Cichorium intybus L. o‘simligi yer ustki qismlari 70 % li etanol ekstraktining o‘tkir zaharliligini eksperimental baholash
Abstract
Tadqiqotda Farg‘ona viloyati hududidan Cichorium intybus L. o‘simligi gullash davrida yig‘ilgan yer ustki qismlarining 70 % li etanol ekstrakti o‘tkir zaharliligi 200–240 g vaznli, 10–12 haftalik 12 ta urg‘ochi oq kalamushda eksperimental baholandi. Ekstraktning 500, 1000, 5000 va 10 000 mg/kg dozalardagi ta’siri 14 kun davomida kuzatildi. 500–5000 mg/kg dozalarda yaqqol zaharlanish belgilari aniqlanmadi. 10 000 mg/kg dozada dastlabki soatlarda tinchlanish va mushaklar holsizligi kuzatilib, ikkinchi kundan boshlab hayvonlarning umumiy holati tiklandi. Kuzatuv davomida o‘lim holatlari qayd etilmadi. Natijalar yuqori dozada vaqtinchalik funksional o‘zgarishlar kuzatilganini ko‘rsatdi.
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References
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